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Termination of Bleeding by a Specific, Anti-catalytic Antibody to Plasmin

BACKGROUND: Excessive, plasmin-mediated fibrinolysis augments bleeding and contributes to death in some patients. Current therapies for fibrinolytic bleeding are limited by modest efficacy, low potency and off-target effects. OBJECTIVES: To determine whether an antibody directed against unique loop...

詳細記述

保存先:
書誌詳細
出版年:J Thromb Haemost
主要な著者: Zhao, Tieqiang, Houng, Aiilyan, Reed, Guy L.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359864/
https://ncbi.nlm.nih.gov/pubmed/31136076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14522
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