MLPA and DNA index improve the molecular diagnosis of childhood B-cell acute lymphoblastic leukemia

Aneuploidy occurs within a significant proportion of childhood B-cell acute lymphoblastic leukemia (B-ALL). Some copy number variations (CNV), associated with novel subtypes of childhood B-ALL, have prognostic significance. A total of 233 childhood B-ALL patients were enrolled into this study. Focal...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Yu, Chih-Hsiang, Lin, Tze-Kang, Jou, Shiann-Tarng, Lin, Chien-Yu, Lin, Kai-Hsin, Lu, Meng-Yao, Chen, Shu-Huey, Cheng, Chao-Neng, Wu, Kang-Hsi, Wang, Shih-Chung, Chang, Hsiu-Hao, Li, Meng-Ju, Ni, Yu-Ling, Su, Yi-Ning, Lin, Dong-Tsamn, Chen, Hsuan-Yu, Harrison, Christine J., Hung, Chia-Cheng, Lin, Shu-Wha, Yang, Yung-Li
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359332/
https://ncbi.nlm.nih.gov/pubmed/32661308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68311-9
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