Targeted sequencing to identify genetic alterations and prognostic markers in pediatric T-cell acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemia (T-ALL) is caused by the accumulation of multiple genetic alterations. To determine the frequency of common genetic mutations and possible prognostic markers in childhood T-ALL, we performed targeted sequencing of 67 genes across 64 cases treated according to Taiw...

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Udgivet i:Sci Rep
Main Authors: Chang, Ya-Hsuan, Yu, Chih-Hsiang, Jou, Shiann-Tarng, Lin, Chien-Yu, Lin, Kai-Hsin, Lu, Meng-Yao, Wu, Kang-Hsi, Chang, Hsiu-Hao, Lin, Dong-Tsamn, Lin, Shu-Wha, Chen, Hsuan-Yu, Yang, Yung-Li
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7804301/
https://ncbi.nlm.nih.gov/pubmed/33436855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-80613-6
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