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High-performance CRISPR-Cas12a genome editing for combinatorial genetic screening
CRISPR-based genetic screening has revolutionized cancer drug target discovery, yet reliable, multiplex gene editing to reveal synergies between gene targets remains a major challenge. Here, we present a simple and robust CRISPR-Cas12a-based approach for combinatorial genetic screening in cancer cel...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7359328/ https://ncbi.nlm.nih.gov/pubmed/32661245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17209-1 |
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