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Evaluation of EED Inhibitors as a Class of PRC2-Targeted Small Molecules for HIV Latency Reversal

[Image: see text] A hallmark of human immunodeficiency type-1 (HIV) infection is the integration of the viral genome into host chromatin, resulting in a latent reservoir that persists despite antiviral therapy or immune response. Thus, key priorities toward eradication of HIV infection are to unders...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:ACS Infect Dis
Prif Awduron: Turner, Anne-Marie W., Dronamraju, Raghuvar, Potjewyd, Frances, James, Katherine S., Winecoff, Daniel K., Kirchherr, Jennifer L., Archin, Nancie M., Browne, Edward P., Strahl, Brian D., Margolis, David M., James, Lindsey I.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2020
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359025/
https://ncbi.nlm.nih.gov/pubmed/32347704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.9b00514
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