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Photodegradation of the H(1) Antihistaminic Topical Drugs Emedastine, Epinastine, and Ketotifen and ROS Tests for Estimations of Their Potent Phototoxicity

In this study, important H(1) antihistaminic drugs, i.e., emedastine (EME), epinastine (EPI), and ketotifen (KET), were irradiated with UV/Vis light (300–800 nm) in solutions of different pH values. Next, they were analyzed by new high performance liquid chromatography (HPLC) methods, in order to es...

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Publicat a:Pharmaceutics
Autors principals: Gumieniczek, Anna, Berecka-Rycerz, Anna, Hubicka, Urszula, Żmudzki, Paweł, Lejwoda, Karolina, Kozyra, Paweł
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7356818/
https://ncbi.nlm.nih.gov/pubmed/32560381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12060560
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