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Development and Validation of Stability-Indicating HPLC Methods for the Estimation of Lomefloxacin and Balofloxacin Oxidation Process under ACVA, H(2)O(2), or KMnO(4) Treatment. Kinetic Evaluation and Identification of Degradation Products by Mass Spectrometry

The oxidation of lomefloxacin (LOM) and balofloxacin (BAL) under the influence of azo initiator of radical reactions of 4,4′-azobis(4-cyanopentanoic acid) (ACVA) and H(2)O(2) was examined. Oxidation using H(2)O(2) was performed at room temperature while using ACVA at temperatures: 40, 50, 60 °C. Add...

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Bibliografiska uppgifter
I publikationen:Molecules
Huvudupphovsmän: Żuromska-Witek, Barbara, Żmudzki, Paweł, Szlósarczyk, Marek, Maślanka, Anna, Hubicka, Urszula
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7697971/
https://ncbi.nlm.nih.gov/pubmed/33187198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25225251
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