Development and Validation of Stability-Indicating HPLC Methods for the Estimation of Lomefloxacin and Balofloxacin Oxidation Process under ACVA, H(2)O(2), or KMnO(4) Treatment. Kinetic Evaluation and Identification of Degradation Products by Mass Spectrometry

The oxidation of lomefloxacin (LOM) and balofloxacin (BAL) under the influence of azo initiator of radical reactions of 4,4′-azobis(4-cyanopentanoic acid) (ACVA) and H(2)O(2) was examined. Oxidation using H(2)O(2) was performed at room temperature while using ACVA at temperatures: 40, 50, 60 °C. Add...

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Vydáno v:Molecules
Hlavní autoři: Żuromska-Witek, Barbara, Żmudzki, Paweł, Szlósarczyk, Marek, Maślanka, Anna, Hubicka, Urszula
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7697971/
https://ncbi.nlm.nih.gov/pubmed/33187198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25225251
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