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Computer-Aided Discovery of New Solubility-Enhancing Drug Delivery System

The poor aqueous solubility of active pharmaceutical ingredients (APIs) places a limit on their therapeutic potential. Cyclodextrins (CDs) have been shown to improve the solubility of APIs, but the magnitude of the improvement depends on the structure of both the CDs and APIs. We have developed quan...

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Détails bibliographiques
Publié dans:Biomolecules
Auteurs principaux: Mizera, Mikołaj, Muratov, Eugene N., Alves, Vinicius M., Tropsha, Alexander, Cielecka-Piontek, Judyta
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7356584/
https://ncbi.nlm.nih.gov/pubmed/32560246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10060913
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