Computer-Aided Design of Cefuroxime Axetil/Cyclodextrin System with Enhanced Solubility and Antimicrobial Activity

This study aimed to investigate changes in the solubility and antimicrobial efficacy of cefuroxime axetil (CA) when incorporated into cyclodextrin (CD). While choosing the CD, the validated in silico model was used. A theoretical model based on docking and molecular mechanics/generalized born surfac...

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Dettagli Bibliografici
Pubblicato in:Biomolecules
Autori principali: Mizera, Mikołaj, Szymanowska, Daria, Stasiłowicz, Anna, Siąkowska, Dominika, Lewandowska, Kornelia, Miklaszewski, Andrzej, Plech, Tomasz, Tykarska, Ewa, Cielecka-Piontek, Judyta
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7023374/
https://ncbi.nlm.nih.gov/pubmed/31878057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10010024
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