Computer-Aided Design of Cefuroxime Axetil/Cyclodextrin System with Enhanced Solubility and Antimicrobial Activity

This study aimed to investigate changes in the solubility and antimicrobial efficacy of cefuroxime axetil (CA) when incorporated into cyclodextrin (CD). While choosing the CD, the validated in silico model was used. A theoretical model based on docking and molecular mechanics/generalized born surfac...

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Bibliografski detalji
Izdano u:Biomolecules
Glavni autori: Mizera, Mikołaj, Szymanowska, Daria, Stasiłowicz, Anna, Siąkowska, Dominika, Lewandowska, Kornelia, Miklaszewski, Andrzej, Plech, Tomasz, Tykarska, Ewa, Cielecka-Piontek, Judyta
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7023374/
https://ncbi.nlm.nih.gov/pubmed/31878057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10010024
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