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Computer-Aided Discovery of New Solubility-Enhancing Drug Delivery System

The poor aqueous solubility of active pharmaceutical ingredients (APIs) places a limit on their therapeutic potential. Cyclodextrins (CDs) have been shown to improve the solubility of APIs, but the magnitude of the improvement depends on the structure of both the CDs and APIs. We have developed quan...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Mizera, Mikołaj, Muratov, Eugene N., Alves, Vinicius M., Tropsha, Alexander, Cielecka-Piontek, Judyta
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7356584/
https://ncbi.nlm.nih.gov/pubmed/32560246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10060913
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