Bicyclic Boronates as Potent Inhibitors of AmpC, the Class C β-Lactamase from Escherichia coli

Resistance to β-lactam antibacterials, importantly via production of β-lactamases, threatens their widespread use. Bicyclic boronates show promise as clinically useful, dual-action inhibitors of both serine- (SBL) and metallo- (MBL) β-lactamases. In combination with cefepime, the bicyclic boronate t...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Biomolecules
मुख्य लेखकों: Lang, Pauline A., Parkova, Anete, Leissing, Thomas M., Calvopiña, Karina, Cain, Ricky, Krajnc, Alen, Panduwawala, Tharindi D., Philippe, Jules, Fishwick, Colin W. G., Trapencieris, Peteris, Page, Malcolm G. P., Schofield, Christopher J., Brem, Jürgen
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI 2020
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7356297/
https://ncbi.nlm.nih.gov/pubmed/32545682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10060899
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