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NHC-catalyzed enantioselective synthesis of β-trifluoromethyl-β-hydroxyamides

The N-heterocyclic carbene (NHC)-catalyzed formal [2 + 2] cycloaddition between α-aroyloxyaldehydes and trifluoroacetophenones, followed by ring opening with an amine or a reducing agent is described. The resulting β-trifluoromethyl-β-hydroxyamide and alcohol products are produced with reasonable di...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Beilstein J Org Chem
मुख्य लेखकों: Davies, Alyn T, Greenhalgh, Mark D, Slawin, Alexandra M Z, Smith, Andrew D
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Beilstein-Institut 2020
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7356285/
https://ncbi.nlm.nih.gov/pubmed/32704323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.16.129
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