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IRE1 Endoribonuclease Activity Modulates Hypoxic HIF-1α Signaling in Human Endothelial Cells

While the role of hypoxia and the induction of the hypoxia inducible factors (HIFs) and the unfolded protein response (UPR) pathways in the cancer microenvironment are well characterized, their roles and relationship in normal human endothelium are less clear. Here, we examined the effects of IRE1 o...

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Detalles Bibliográficos
Publicado en:Biomolecules
Autores principales: Moszyńska, Adrianna, Collawn, James F., Bartoszewski, Rafal
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355874/
https://ncbi.nlm.nih.gov/pubmed/32545307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10060895
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