Primary endothelial cell–specific regulation of hypoxia-inducible factor (HIF)-1 and HIF-2 and their target gene expression profiles during hypoxia

During hypoxia, a cellular adaptive response activates hypoxia-inducible factors (HIFs; HIF-1 and HIF-2) that respond to low tissue-oxygen levels and induce the expression of a number of genes that promote angiogenesis, energy metabolism, and cell survival. HIF-1 and HIF-2 regulate endothelial cell...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Bartoszewski, Rafal, Moszyńska, Adrianna, Serocki, Marcin, Cabaj, Aleksandra, Polten, Andreas, Ochocka, Renata, Dell’Italia, Louis, Bartoszewska, Sylwia, Króliczewski, Jarosław, Dąbrowski, Michał, Collawn, James F.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593883/
https://ncbi.nlm.nih.gov/pubmed/30917010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802650RR
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