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Application of the Gastrointestinal Simulator (GIS) Coupled with In Silico Modeling to Measure the Impact of Coca-Cola(®) on the Luminal and Systemic Behavior of Loratadine (BCS Class 2b)
In the present work, we explored if Coca-Cola(®) had a beneficial impact on the systemic outcome of the weakly basic drug loratadine (Wal-itin(®), immediate-release formulation, 10 mg, generic drug product). To map the contribution of underlying physiological variables that may positively impact the...
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| Опубликовано в: : | Pharmaceutics |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
MDPI
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7355706/ https://ncbi.nlm.nih.gov/pubmed/32570975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12060566 |
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