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Microscale Thermophoresis as a Screening Tool to Predict Melanin Binding of Drugs

Interactions between drugs and melanin pigment may have major impacts on pharmacokinetics. Therefore, melanin binding can modify the efficacy and toxicity of medications in ophthalmic and other disease of pigmented tissues, such as melanoma. As melanin is present in many pigmented tissues in the hum...

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Bibliografiske detaljer
Udgivet i:Pharmaceutics
Main Authors: Hellinen, Laura, Bahrpeyma, Sina, Rimpelä, Anna-Kaisa, Hagström, Marja, Reinisalo, Mika, Urtti, Arto
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355663/
https://ncbi.nlm.nih.gov/pubmed/32560065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12060554
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