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Microscale Thermophoresis as a Screening Tool to Predict Melanin Binding of Drugs

Interactions between drugs and melanin pigment may have major impacts on pharmacokinetics. Therefore, melanin binding can modify the efficacy and toxicity of medications in ophthalmic and other disease of pigmented tissues, such as melanoma. As melanin is present in many pigmented tissues in the hum...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Hellinen, Laura, Bahrpeyma, Sina, Rimpelä, Anna-Kaisa, Hagström, Marja, Reinisalo, Mika, Urtti, Arto
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355663/
https://ncbi.nlm.nih.gov/pubmed/32560065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12060554
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