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The (+)-Brevipolide H Displays Anticancer Activity against Human Castration-Resistant Prostate Cancer: The Role of Oxidative Stress and Akt/mTOR/p70S6K-Dependent Pathways in G1 Checkpoint Arrest and Apoptosis

Because conventional chemotherapy is not sufficiently effective against prostate cancer, various examinations have been performed to identify anticancer activity of naturally occurring components and their mechanisms of action. The (+)-brevipolide H, an α-pyrone-based natural compound, induced poten...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Sheng, Yi-Hua, Leu, Wohn-Jenn, Chen, Ching-Nung, Hsu, Jui-Ling, Liu, Ying-Tung, Hsu, Lih-Ching, Hou, Duen-Ren, Guh, Jih-Hwa
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355498/
https://ncbi.nlm.nih.gov/pubmed/32630532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25122929
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