Bleeding is increased in amyloid precursor protein knockout mouse

BACKGROUND: Amyloid precursor protein (APP) is highly expressed in platelets. APP is the precursor to amyloid beta (Aβ) peptides that accumulate in cerebral amyloid angiopathy and plaques in Alzheimer disease. APP and its metabolites interact with many components of the coagulation system, and have...

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Bibliografiske detaljer
Udgivet i:Res Pract Thromb Haemost
Main Authors: Mazinani, Nima, Strilchuk, Amy W., Baylis, James R., Hur, Woosuk S., Jefferies, Wilfred A., Kastrup, Christian J.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Original Articles: Hemostasis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7354397/
https://ncbi.nlm.nih.gov/pubmed/32685890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rth2.12375
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