Bleeding is increased in amyloid precursor protein knockout mouse

BACKGROUND: Amyloid precursor protein (APP) is highly expressed in platelets. APP is the precursor to amyloid beta (Aβ) peptides that accumulate in cerebral amyloid angiopathy and plaques in Alzheimer disease. APP and its metabolites interact with many components of the coagulation system, and have...

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Detaylı Bibliyografya
Yayımlandı:Res Pract Thromb Haemost
Asıl Yazarlar: Mazinani, Nima, Strilchuk, Amy W., Baylis, James R., Hur, Woosuk S., Jefferies, Wilfred A., Kastrup, Christian J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2020
Konular:
Original Articles: Hemostasis
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7354397/
https://ncbi.nlm.nih.gov/pubmed/32685890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rth2.12375
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