FOXM1 nuclear transcription factor translocates into mitochondria and inhibits oxidative phosphorylation

Forkhead box M1 (FOXM1), a nuclear transcription factor that activates cell cycle regulatory genes, is highly expressed in a majority of human cancers. The function of FOXM1 independent of nuclear transcription is unknown. In the present study, we found the FOXM1 protein inside the mitochondria. Usi...

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Vydáno v:Mol Biol Cell
Hlavní autoři: Black, Markaisa, Arumugam, Paritha, Shukla, Samriddhi, Pradhan, Arun, Ustiyan, Vladimir, Milewski, David, Kalinichenko, Vladimir V., Kalin, Tanya V.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7353143/
https://ncbi.nlm.nih.gov/pubmed/32348194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-07-0413
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