SPDEF Inhibits Prostate Carcinogenesis by Disrupting a Positive Feedback Loop in Regulation of the Foxm1 Oncogene

SAM-pointed domain-containing ETS transcription factor (SPDEF) is expressed in normal prostate epithelium. While its expression changes during prostate carcinogenesis (PCa), the role of SPDEF in prostate cancer remains controversial due to the lack of genetic mouse models. In present study, we gener...

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Detalhes bibliográficos
Main Authors: Cheng, Xin-Hua, Black, Markaisa, Ustiyan, Vladimir, Le, Tien, Fulford, Logan, Sridharan, Anusha, Medvedovic, Mario, Kalinichenko, Vladimir V., Whitsett, Jeffrey A., Kalin, Tanya V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177813/
https://ncbi.nlm.nih.gov/pubmed/25254494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004656
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