SPDEF Inhibits Prostate Carcinogenesis by Disrupting a Positive Feedback Loop in Regulation of the Foxm1 Oncogene

SAM-pointed domain-containing ETS transcription factor (SPDEF) is expressed in normal prostate epithelium. While its expression changes during prostate carcinogenesis (PCa), the role of SPDEF in prostate cancer remains controversial due to the lack of genetic mouse models. In present study, we gener...

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Bibliografiska uppgifter
Huvudupphovsmän: Cheng, Xin-Hua, Black, Markaisa, Ustiyan, Vladimir, Le, Tien, Fulford, Logan, Sridharan, Anusha, Medvedovic, Mario, Kalinichenko, Vladimir V., Whitsett, Jeffrey A., Kalin, Tanya V.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177813/
https://ncbi.nlm.nih.gov/pubmed/25254494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004656
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