Loss of FOXM1 in macrophages promotes pulmonary fibrosis by activating p38 MAPK signaling pathway

Idiopathic pulmonary fibrosis (IPF) is a chronic disease with high mortality and is refractory to treatment. Pulmonary macrophages can both promote and repress fibrosis, however molecular mechanisms regulating macrophage functions during fibrosis remain poorly understood. FOXM1 is a transcription fa...

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Udgivet i:PLoS Genet
Main Authors: Goda, Chinmayee, Balli, David, Black, Markaisa, Milewski, David, Le, Tien, Ustiyan, Vladimir, Ren, Xiaomeng, Kalinichenko, Vladimir V., Kalin, Tanya V.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7173935/
https://ncbi.nlm.nih.gov/pubmed/32271749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008692
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