Loss of FOXM1 in macrophages promotes pulmonary fibrosis by activating p38 MAPK signaling pathway

Idiopathic pulmonary fibrosis (IPF) is a chronic disease with high mortality and is refractory to treatment. Pulmonary macrophages can both promote and repress fibrosis, however molecular mechanisms regulating macrophage functions during fibrosis remain poorly understood. FOXM1 is a transcription fa...

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Détails bibliographiques
Publié dans:PLoS Genet
Auteurs principaux: Goda, Chinmayee, Balli, David, Black, Markaisa, Milewski, David, Le, Tien, Ustiyan, Vladimir, Ren, Xiaomeng, Kalinichenko, Vladimir V., Kalin, Tanya V.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7173935/
https://ncbi.nlm.nih.gov/pubmed/32271749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008692
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