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The Hepatotoxicity of Alantolactone and Germacrone: Their Influence on Cholesterol and Lipid Metabolism in Differentiated HepaRG Cells

The sesquiterpenes alantolactone (ATL) and germacrone (GER) are potential anticancer agents of natural origin. Their toxicity and biological activity have been evaluated using the differentiated HepaRG (dHepaRG) cells, a hepatocyte-like model. The half-maximal inhibitory concentrations of cell viabi...

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Publicat a:Nutrients
Autors principals: Zárybnický, Tomáš, Matoušková, Petra, Skálová, Lenka, Boušová, Iva
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7353089/
https://ncbi.nlm.nih.gov/pubmed/32521813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu12061720
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