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HepaRG CELLS: A HUMAN MODEL TO STUDY MECHANISMS OF ACETAMINOPHEN HEPATOTOXICITY
Acetaminophen (APAP) overdose is the leading cause of acute liver failure in Western countries. In the last four decades, much progress has been made in our understanding of APAP-induced liver injury through rodent studies. However, some differences exist in the time course of injury between rodents...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3073317/ https://ncbi.nlm.nih.gov/pubmed/21319200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24132 |
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