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Bile Acid-Induced Toxicity in HepaRG Cells Recapitulates the Response in Primary Human Hepatocytes

Cholestatic liver injury is a pathological component of numerous disease states. Much of the current literature on cholestatic liver injury is derived from in vitro studies using rodent hepatocytes or cell lines transfected with bile acid (BA) uptake transporters. While these studies demonstrate BA-...

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Bibliografski detalji
Izdano u:Basic Clin Pharmacol Toxicol
Glavni autori: Woolbright, Benjamin L., McGill, Mitchell R., Yan, Huimin, Jaeschke, Hartmut
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713390/
https://ncbi.nlm.nih.gov/pubmed/26176423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcpt.12449
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