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Inter-Individual Variability in Acute Toxicity of R-Pulegone and R-Menthofuran in Human Liver Slices and Their Influence on miRNA Expression Changes in Comparison to Acetaminophen

Monoterpenes R-pulegone (PUL) and R-menthofuran (MF), abundant in the Lamiaceae family, are frequently used in herb and food products. Although their hepatotoxicity was shown in rodent species, information about their effects in human liver has been limited. The aim of our study was to test the effe...

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Sonraí Bibleagrafaíochta
Foilsithe in:Int J Mol Sci
Main Authors: Zárybnický, Tomáš, Matoušková, Petra, Lancošová, Bibiána, Šubrt, Zdeněk, Skálová, Lenka, Boušová, Iva
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032148/
https://ncbi.nlm.nih.gov/pubmed/29921785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19061805
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