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How and Why Are Cancers Acidic? Carbonic Anhydrase IX and the Homeostatic Control of Tumour Extracellular pH

The acidic tumour microenvironment is now recognized as a tumour phenotype that drives cancer somatic evolution and disease progression, causing cancer cells to become more invasive and to metastasise. This property of solid tumours reflects a complex interplay between cellular carbon metabolism and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Lee, Shen-Han, Griffiths, John R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352839/
https://ncbi.nlm.nih.gov/pubmed/32570870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12061616
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