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How and Why Are Cancers Acidic? Carbonic Anhydrase IX and the Homeostatic Control of Tumour Extracellular pH

The acidic tumour microenvironment is now recognized as a tumour phenotype that drives cancer somatic evolution and disease progression, causing cancer cells to become more invasive and to metastasise. This property of solid tumours reflects a complex interplay between cellular carbon metabolism and...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Lee, Shen-Han, Griffiths, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352839/
https://ncbi.nlm.nih.gov/pubmed/32570870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12061616
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