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Recombinant Adeno-Associated Viral Vectors (rAAV)-Vector Elements in Ocular Gene Therapy Clinical Trials and Transgene Expression and Bioactivity Assays

Inherited retinal dystrophies and optic neuropathies cause chronic disabling loss of visual function. The development of recombinant adeno-associated viral vectors (rAAV) gene therapies in all disease fields have been promising, but the translation to the clinic has been slow. The safety and efficac...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Int J Mol Sci
Päätekijät: Buck, Thilo M., Wijnholds, Jan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352801/
https://ncbi.nlm.nih.gov/pubmed/32545533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124197
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