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An inducible system for highly efficient production of recombinant adeno-associated virus (rAAV) vectors in insect Sf9 cells
Production of clinical-grade gene therapy vectors for human trials remains a major hurdle in advancing cures for a number of otherwise incurable diseases. We describe a system based on a stably transformed insect cell lines harboring helper genes required for vector production. Integrated genes rema...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2654393/ https://ncbi.nlm.nih.gov/pubmed/19279219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810614106 |
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