Successful Production of Pseudotyped rAAV Vectors Using a Modified Baculovirus Expression System

Scalable production of rAAV vectors remains a major obstacle to the clinical application of this prototypical gene therapy vector. A recently developed baculovirus-based production protocol (M. Urabe et al., 2002, Hum. Gene Ther. 13, 1935–1943) found limited applications due to the system’s design....

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Main Authors: Kohlbrenner, Erik, Aslanidi, George, Nash, Kevin, Shklyaev, Stanislav, Campbell-Thompson, Martha, Byrne, Barry J., Snyder, Richard O., Muzyczka, Nicholas, Warrington, Kenneth H., Zolotukhin, Sergei
Formato: Artigo
Idioma:Inglês
Publicado: 2005
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1351154/
https://ncbi.nlm.nih.gov/pubmed/16213797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2005.08.018
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