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The Modified Phenanthridine PJ34 Unveils an Exclusive Cell-Death Mechanism in Human Cancer Cells

This overview summarizes recent data disclosing the efficacy of the PARP inhibitor PJ34 in exclusive eradication of a variety of human cancer cells without impairing healthy proliferating cells. Its cytotoxic activity in cancer cells is attributed to the insertion of specific un-repairable anomalies...

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Sonraí Bibleagrafaíochta
Foilsithe in:Cancers (Basel)
Príomhúdar: Cohen-Armon, Malka
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352794/
https://ncbi.nlm.nih.gov/pubmed/32575437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12061628
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