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The phenanthrene derivative PJ34 exclusively eradicates human pancreatic cancer cells in xenografts

Recent reports demonstrate an exclusive eradication of a variety of human cancer cells by the modified phenanthridine PJ34. Their eradication during mitosis is attributed to PJ34 preventing NuMA clustering in the mitotic spindle poles of human malignant cells, which is crucial for their normal mitos...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Visochek, Leonid, Atias, Dikla, Spektor, Itay, Castiel, Asher, Golan, Talia, Cohen-Armon, Malka
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817443/
https://ncbi.nlm.nih.gov/pubmed/31692907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27268
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