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The phenanthrene derivative PJ34 exclusively eradicates human pancreatic cancer cells in xenografts

Recent reports demonstrate an exclusive eradication of a variety of human cancer cells by the modified phenanthridine PJ34. Their eradication during mitosis is attributed to PJ34 preventing NuMA clustering in the mitotic spindle poles of human malignant cells, which is crucial for their normal mitos...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Visochek, Leonid, Atias, Dikla, Spektor, Itay, Castiel, Asher, Golan, Talia, Cohen-Armon, Malka
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817443/
https://ncbi.nlm.nih.gov/pubmed/31692907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27268
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