The Metabolism of Epoxyeicosatrienoic Acids by Soluble Epoxide Hydrolase Is Protective against the Development of Vascular Calcification

This study addressed the hypothesis that soluble epoxide hydrolase (sEH), which metabolizes endothelium-derived epoxyeicosatrienoic acids, plays a role in vascular calcification. The sEH inhibitor trans-4-(4-(3-adamantan-1-yl-ureido)-cyclohexyloxy)-benzoic acid (t-AUCB) potentiated the increase in c...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Varennes, Olivier, Mentaverri, Romuald, Duflot, Thomas, Kauffenstein, Gilles, Objois, Thibaut, Lenglet, Gaëlle, Avondo, Carine, Morisseau, Christophe, Brazier, Michel, Kamel, Saïd, Six, Isabelle, Bellien, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352784/
https://ncbi.nlm.nih.gov/pubmed/32560362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124313
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