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The antiinflammatory effect of laminar flow: The role of PPARγ, epoxyeicosatrienoic acids, and soluble epoxide hydrolase

We previously reported that laminar flow activates peroxisome proliferator-activated receptor γ (PPARγ) in vascular endothelial cells in a ligand-dependent manner that involves phospholipase A2 and cytochrome P450 epoxygenases. In this study, we investigated whether epoxyeicosatrienoic acids (EETs),...

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Hlavní autoři: Liu, Yi, Zhang, Yingjia, Schmelzer, Kara, Lee, Tzong-Shyuan, Fang, Xiang, Zhu, Yi, Spector, Arthur A., Gill, Sarjeet, Morisseau, Christophe, Hammock, Bruce D., Shyy, John Y.-J.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2005
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276614/
https://ncbi.nlm.nih.gov/pubmed/16267130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508081102
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