Roles of Histone Deacetylases and Inhibitors in Anticancer Therapy

Histones are the main structural proteins of eukaryotic chromatin. Histone acetylation/ deacetylation are the epigenetic mechanisms of the regulation of gene expression and are catalyzed by histone acetyltransferases (HAT) and histone deacetylases (HDAC). These epigenetic alterations of DNA structur...

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Sparad:
Bibliografiska uppgifter
I publikationen:Cancers (Basel)
Huvudupphovsmän: Verza, Flávia Alves, Das, Umashankar, Fachin, Ana Lúcia, Dimmock, Jonathan R., Marins, Mozart
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2020
Ämnen:
Review
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352721/
https://ncbi.nlm.nih.gov/pubmed/32585896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12061664
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