Nifedipine Exacerbates Lipogenesis in the Kidney via KIM-1, CD36, and SREBP Upregulation: Implications from an Animal Model for Human Study

Dysregulation of fatty acid oxidation and accumulation of fatty acids can cause kidney injury. Nifedipine modulates lipogenesis-related transcriptional factor SREBP-1/2 in proximal tubular cells by inhibiting the Adenosine 5‘-monophosphate (AMP)-activated protein kinase (AMPK) pathway in vitro. Howe...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Lin, Yen-Chung, Wang, Jhih-Cheng, Wu, Mai-Szu, Lin, Yuh-Feng, Chen, Chang-Rong, Chen, Chang-Yu, Chen, Kuan-Chou, Peng, Chiung-Chi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352626/
https://ncbi.nlm.nih.gov/pubmed/32575412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124359
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items