Nifedipine Modulates Renal Lipogenesis via the AMPK-SREBP Transcriptional Pathway

Lipid accumulation in renal cells has been implicated in the pathogenesis of obesity-related kidney disease, and lipotoxicity in the kidney can be a surrogate marker for renal failure or renal fibrosis. Fatty acid oxidation provides energy to renal tubular cells. Ca(2+) is required for mitochondrial...

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Publicat a:Int J Mol Sci
Autors principals: Lin, Yen-Chung, Wu, Mai-Szu, Lin, Yuh-Feng, Chen, Chang-Rong, Chen, Chang-Yu, Chen, Chang-Jui, Shen, Che-Chou, Chen, Kuan-Chou, Peng, Chiung-Chi
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6480582/
https://ncbi.nlm.nih.gov/pubmed/30934807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20071570
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