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Nifedipine Modulates Renal Lipogenesis via the AMPK-SREBP Transcriptional Pathway
Lipid accumulation in renal cells has been implicated in the pathogenesis of obesity-related kidney disease, and lipotoxicity in the kidney can be a surrogate marker for renal failure or renal fibrosis. Fatty acid oxidation provides energy to renal tubular cells. Ca(2+) is required for mitochondrial...
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Publicado no: | Int J Mol Sci |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
MDPI
2019
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6480582/ https://ncbi.nlm.nih.gov/pubmed/30934807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20071570 |
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