Non-invasive characterization of amyotrophic lateral sclerosis in a hTDP-43(A315T) mouse model: A PET-MR study

Currently TAR DNA binding protein 43 (TDP-43) pathology, underlying Amyotrophic Lateral Sclerosis (ALS), remains poorly understood which hinders both clinical diagnosis and drug discovery efforts. To better comprehend the disease pathophysiology, positron emission tomography (PET) and multi-parametr...

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Udgivet i:Neuroimage Clin
Main Authors: Weerasekera, Akila, Crabbé, Melissa, Tomé, Sandra O., Gsell, Willy, Sima, Diana, Casteels, Cindy, Dresselaers, Tom, Deroose, Christophe, Van Huffel, Sabine, Rudolf Thal, Dietmar, Van Damme, Philip, Himmelreich, Uwe
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352080/
https://ncbi.nlm.nih.gov/pubmed/32653817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2020.102327
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