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CT-2A neurospheres-derived high-grade glioma in mice: a new model to address tumor stem cells and immunosuppression

Recently, several promising treatments for high-grade gliomas (HGGs) failed to provide significant benefit when translated from the preclinical setting to patients. Improving the animal models is fundamental to overcoming this translational gap. To address this need, we developed and comprehensively...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Riva, Matteo, Wouters, Roxanne, Weerasekera, Akila, Belderbos, Sarah, Nittner, David, Thal, Dietmar R., Baert, Thaïs, Giovannoni, Roberto, Gsell, Willy, Himmelreich, Uwe, Van Ranst, Marc, Coosemans, An
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777368/
https://ncbi.nlm.nih.gov/pubmed/31511246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.044552
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