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CT-2A neurospheres-derived high-grade glioma in mice: a new model to address tumor stem cells and immunosuppression

Recently, several promising treatments for high-grade gliomas (HGGs) failed to provide significant benefit when translated from the preclinical setting to patients. Improving the animal models is fundamental to overcoming this translational gap. To address this need, we developed and comprehensively...

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Bibliografiske detaljer
Udgivet i:Biol Open
Main Authors: Riva, Matteo, Wouters, Roxanne, Weerasekera, Akila, Belderbos, Sarah, Nittner, David, Thal, Dietmar R., Baert, Thaïs, Giovannoni, Roberto, Gsell, Willy, Himmelreich, Uwe, Van Ranst, Marc, Coosemans, An
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777368/
https://ncbi.nlm.nih.gov/pubmed/31511246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.044552
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