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Soluble uric acid induces inflammation via TLR4/NLRP3 pathway in intestinal epithelial cells
OBJECTIVE(S): Hyperuricemia is a risk for cardiovascular and metabolic diseases, but the mechanism is ambiguous. Increased intestinal permeability is correlated with metabolic syndrome risk factors. Intestinal epithelial cells play a pivotal role in maintaining intestinal permeability. Uric acid is...
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| 出版年: | Iran J Basic Med Sci |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Mashhad University of Medical Sciences
2020
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7351448/ https://ncbi.nlm.nih.gov/pubmed/32695290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2020.44948.10482 |
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