Soluble uric acid induces inflammation via TLR4/NLRP3 pathway in intestinal epithelial cells

OBJECTIVE(S): Hyperuricemia is a risk for cardiovascular and metabolic diseases, but the mechanism is ambiguous. Increased intestinal permeability is correlated with metabolic syndrome risk factors. Intestinal epithelial cells play a pivotal role in maintaining intestinal permeability. Uric acid is...

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Библиографические подробности
Опубликовано в: :Iran J Basic Med Sci
Главные авторы: Ma, Chunling, Yang, Xiaomin, Lv, Qiulan, Yan, Zhimei, Chen, Zeqing, Xu, Daxing, Liu, Xiu, Yang, Wan, Xing, Shichao
Формат: Artigo
Язык:Inglês
Опубликовано: Mashhad University of Medical Sciences 2020
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7351448/
https://ncbi.nlm.nih.gov/pubmed/32695290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2020.44948.10482
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