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The Function of Mitochondrial Calcium Uniporter at the Whole-Cell and Single Mitochondrion Levels in WT, MICU1 KO, and MICU2 KO Cells

Mitochondrial Ca(2+) ([Ca(2+)](M)) uptake through its Ca(2+) uniporter (MCU) is central to many cell functions such as bioenergetics, spatiotemporal organization of Ca(2+) signals, and apoptosis. MCU activity is regulated by several intrinsic proteins including MICU1, MICU2, and EMRE. While signific...

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Bibliografiske detaljer
Udgivet i:Cells
Main Authors: Shah, Syed Islamuddin, Ullah, Ghanim
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7349584/
https://ncbi.nlm.nih.gov/pubmed/32580385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061520
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