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MICU1 and MICU2 play nonredundant roles in the regulation of the mitochondrial calcium uniporter

The mitochondrial uniporter is a selective Ca(2+) channel regulated by MICU1, an EF hand-containing protein in the organelle's intermembrane space. MICU1 physically associates with and is co-expressed with a paralog, MICU2. To clarify the function of MICU1 and its relationship to MICU2, we used...

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Detalhes bibliográficos
Main Authors: Kamer, Kimberli J, Mootha, Vamsi K
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989696/
https://ncbi.nlm.nih.gov/pubmed/24503055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embr.201337946
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