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Nucleophosmin 1 Mutations in Acute Myeloid Leukemia
Nucleophosmin (NPM1) is a ubiquitously expressed nucleolar protein involved in ribosome biogenesis, the maintenance of genomic integrity and the regulation of the ARF-p53 tumor-suppressor pathway among multiple other functions. Mutations in the corresponding gene cause a cytoplasmic dislocation of t...
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| Udgivet i: | Genes (Basel) |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7348733/ https://ncbi.nlm.nih.gov/pubmed/32545659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11060649 |
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